Table 4 Association of variables with abnormalities in semen analysis
Variable | n | Univariable analysis | Final multivariable model (n = 17) | |||||
|---|---|---|---|---|---|---|---|---|
OR | 95% CI | p-value | OR | 95% CI | p-value | |||
Age of patient at inclusion | 17 | For the increase of one year | 1.16 | 1.01–1.33 | 0.0403 | 1.19 | 0.98–1.45 | 0.0854 |
Severity of FD | 17 | 1 - Severe vs 0 - Non severe | 1.17 | 0.12–10.99 | 0.8927 | |||
Kidney failure | 17 | 1 - Yes vs 0 - No | 1.33 | 0.19–9.31 | 0.7717 | |||
Hypertrophic cardiomyopathy | 17 | 1 - Yes vs 0 - No | 0.48 | 0.07–3.35 | 0.4592 | |||
Duration of replacement treatment | 17 | For the increase of 1 year | 1.26 | 0.96–1.65 | 0.0965 | 1.28 | 0.93–1.74 | 0.1263 |
Professional or domestic exposure | 17 | 1 - Yes vs 0 - No | 0.87 | 0.05–16.74 | 0.9292 | |||
Tobacco consumption | 17 | 1 - Yes vs 0 - No | 0.48 | 0.06–3.99 | 0.4939 | |||
Alcohol consumption | 17 | 1 - Yes vs 0 - No | 0.30 | 0.04–2.2 | 0.2363 | |||
Duration of FD from first symptoms | 16 | For the increase of 1 year | 1.05 | 0.96–1.16 | 0.2866 | |||
Age of patient at the beginning of replacement therapy | 17 | For the increase of 1 year | 1.09 | 0.98–1.22 | 0.1222 | |||
Active compound | 17 | 1 - α-galactosidase vs 2 - ß-galactosidase | 2.00 | 0.28–14.2 | 0.4882 | 3.77 | 0.21–66.8 | 0.3662 |