Table 1 Differential expression of Sertoli cell specific genes in Ad- versus Ad+ group (Ad-/Ad+) and in the GnRHa treated versus untreated group (GnRHa)
From: Curative GnRHa treatment has an unexpected repressive effect on Sertoli cell specific genes
Gene ID | Name | FC Ad-/Ad+ | logFC Ad-/Ad+ | FDR Ad-/Ad+ | FC GnRHa | logFC GnRHa | FDR GnRHa |
|---|---|---|---|---|---|---|---|
AMH | Anti-Mullerian Hormone | - | n.s. | n.s. | - | n.s. | n.s. |
AR | Androgen Receptor | - | n.s. | n.s. | 1.5 | -0.5821 | 0.0126 |
BMP4 | Bone Morphogenetic Protein 4 | - | n.s. | n.s. | - | n.s. | n.s. |
BMP6 | Bone Morphogenetic Protein 6 | 1.7 | -0.7612 | 0.0030 | - | n.s. | n.s. |
CALB2 | Calbindin 2 | - | n.s. | n.s. | 2.2 | -1.1556 | 0.0034 |
CDKN1B | Cyclin-Dependent Kinase inhibitor 1B (p27, Kip1) | - | n.s. | n.s. | 1.7 | -0.7845 | 0.0016 |
CLDN11 | Claudin 11 | - | n.s. | n.s. | 1.8 | -0.8315 | 0.0011 |
CLU | Clusterin | - | n.s. | n.s. | 1.9 | -0.9548 | 0.0006 |
CREB1 | cAMP Responsive Element Binding protein 1 | 1.1 | 0.2000 | 0.0489 | 1.6 | -0.6888 | 0.0041 |
CTSL | Cathepsin L | - | n.s. | n.s. | 1.7 | -0.7492 | 0.0020 |
DES | Desmin | 2.8 | -1.4882 | 0.0014 | - | n.s. | n.s. |
DHH | Desert Hedgehog | - | n.s. | n.s. | - | n.s. | n.s. |
DMRT1 | Doublesex and Mab-3 Related Transcription factor 1 | - | n.s. | n.s. | 1.7 | -0.7838 | 0.0010 |
FAS | Fas cell surface death receptor | - | n.s. | n.s. | - | n.s. | n.s. |
FASLG | Fas Ligand (TNF superfamily, member 6) | - | n.d. | n.d. | 5.0 | 2.3154 | 0.0031 |
FSHR | Follicle stimulating hormone receptor | 1.4 | 0.4915 | 0.0363 | - | n.s. | n.s. |
FGF2 | Fibroblast Growth Factor 2 | - | n.s. | n.s. | - | n.s. | n.s. |
FGF9 | Fibroblast Growth Factor 9 | 2.1 | -1.0605 | 0.0016 | - | n.s. | n.s. |
GATA1 | GATA binding protein 1 (globin transcription factor 1) | - | n.d. | n.d. | - | n.d. | n.d. |
GATA4 | GATA binding protein 4 | - | n.s. | n.s. | - | n.s. | n.s. |
GJA1/CX43 | Gap Junction protein, Alpha 1/Connexin 43 | 1.3 | 0.4018 | 0.0324 | 1.9 | -0.9516 | 0.0002 |
GDNF | Glial cell Derived Neurotrophic Factor | - | n.s. | n.s. | 2.8 | 1.4687 | 0.0036 |
INHA | Inhibin, alpha | - | n.s. | n.s. | 1.8 | -0.8158 | 0.0023 |
INHBA | Inhibin, Beta A | - | n.s. | n.s. | 1.6 | -0.6363 | 0.0124 |
INHBB | Inhibin, Beta B | - | n.s. | n.s. | 1.6 | -0.6616 | 0.0058 |
KATNAL1 | Katanin p60 subunit A-like 1 | - | n.s. | n.s. | 1.7 | -0.7782 | 0.0012 |
KITLG | KIT Ligand | - | n.s. | n.s. | 2.1 | -1.0995 | 0.0001 |
KRT18 | Keratin 18, type I | - | n.s. | n.s. | 1.5 | -0.5730 | 0.0176 |
NR5A1/SF1 | Nuclear Receptor subfamily 5, group A, member 1 | - | n.s. | n.s. | - | n.s. | n.s. |
PTGDS | Prostaglandin D2 Synthase | - | n.s. | n.s. | - | n.s. | n.s. |
SERPINA5 | Serpin Family A Member 5 | - | n.s. | n.s. | 1.7 | -0.7511 | 0.0076 |
SOX8 | SRY (sex determining region Y)-box 8 | 2.8 | -1.4641 | 0.0003 | - | n.s. | n.s. |
SOX9 | SRY (sex determining region Y)-box 9 | 1.4 | 0.4983 | 0.0300 | - | n.s. | n.s. |
SRY | Sex determining Region Y | - | n.s. | n.s. | - | n.s. | n.s. |
TF | Transferrin | - | n.s. | n.s. | - | n.s. | n.s. |
TJP1/ZO1 | Tight Junction Protein 1/Zona Occludens 1 | - | n.s. | n.s. | 1.6 | -0.6824 | 0.0102 |
VIM | Vimentin | - | n.s. | n.s. | 1.5 | -0.5901 | 0.0352 |
WT1 | Wilms tumor 1 | - | n.s. | n.s. | 1.5 | -0.5654 | 0.0180 |
ZFPM1/FOG1 | Zinc Finger Protein, FOG family member 2 | - | n.s. | n.s. | - | n.s. | n.s. |
ZFPM2/FOG2 | Zinc Finger Protein, FOG family member 2 | 1.3 | 0.3695 | 0.0240 | - | n.s. | n.s. |