From: Sperm quality and paternal age: effect on blastocyst formation and pregnancy rates
Paternal age (years) | 20 < Age < 29 | 30 < Age < 39 | 40 < Age < 50 | Age > 51 | P value |
---|---|---|---|---|---|
Mean maternal age (years ± SD) | 29.39 ± 5.11 | 34.22 ± 4.18 | 37.08 ± 3.43 | 37.00 ± 5.77 | <0.0001 |
Number of IVF | 114 | 524 | 211 | 10 | |
Mean number of inseminated oocytes ± SD | 10.11 ± 5.72 | 9.99 ± 5.44 | 9.31 ± 5.26 | 7.30 ± 6.17 | 0.1024 |
Fertilization rate (%) | 64.01 | 67.66 | 65.99 | 42.46 | <0.0001 |
Mean number of embryos at day 2 ± SD | 6.76 ± 4.29 | 7.01 ± 4.58 | 6.38 ± 4.12 | 3.40 ± 4.67 | 0.0104 |
Mean number of embryos at day 3 ± SD | 6.13 ± 3.88 | 6.31 ± 4.17 | 5.72 ± 4.02 | 2.90 ± 4.15 | 0.0048 |
Mean number of embryos in prolonged culture ± SD | 3.51 ± 3.68 | 4.09 ± 4.16 | 3.60 ± 3.86 | 1.60 ± 3.53 | 0.0408 |
Mean number of obtained blastocysts ± SD | 1.74 ± 2.35 | 2.25 ± 2.73 | 1.78 ± 2.30 | 0.90 ± 2.02 | 0.0319 |
Rate of blastocyst formation (%) | 49.50 | 54.97 | 49.41 | 56.25 | 0.0255 |
Mean number of transferred blastocysts ± SD | 0.053 ± 0.224 | 0.113 ± 0.322 | 0.118 ± 0.324 | 0.000 ± 0.000 | 0,6987 |
Mean number of frozen blastocysts ± SD | 0.667 ± 1.420 | 1.040 ± 1.830 | 1.070 ± 1.780 | 0.700 ± 1.640 | 0.3081 |
Rate of useful blastocysts (%) | 41.41 | 51.10 | 66.93 | 77.78 | <0.0001 |
Rate of clinical pregnancies (%) | 28.60 | 38.90 | 39.70 | 14.30 | 0.1151 |
Rate of miscarriages (%) | 17.90 | 18.60 | 34.40 | NR | 0.3504 |