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Table 4 Comparison of the levels of sex hormones and lipid levels in serum in participants in stage CKD 1–5

From: Testosterone and gonadotropins but not SHBG vary with CKD stages in young and middle aged men

 

CKD 1

CKD 2

CKD 3

CKD 4

CKD 5

p

N = 101

23

20

27

13

18

 

S- Testosterone (nmol/L)

14.89 ± 3.91

14.10 ± 4.15

13.22 ± 3.81

10.81 ± 4.53

8.82 ± 3.81

<0.01

S-SHBG (nmol/L)

29.56 ± 12.73

35.50 ± 13.03

34.55 ± 13.51

33.07 ± 12.9

28.55 ± 13.47

ns

Free testosterone nmol/L

0.33 ± 0.10

0.28 ± 0.06

0.25 ± 0.05

0.19 ± 0.07

0.19 ± 0.08

<0.01

S-LH (U/L)

4.16 ± 2.07

3.33 ± 1.40

6.77 ± 4.22

6.50 ± 2.71

9.43 ± 7.60

<0.01

S-FSH (U/L)

3.67 ± 2.65

3.67 ± 2.06

6.85 ± 4.04

5.21 ± 4.82

13.51 ± 6.98

ns

S-Prolactin (μg/L)

7.76 ± 2.04

8.54 ± 3.36

9.24 ± 2.47

16.50 ± 12.54

17.41 ± 2.13

<0.01

S-Cholesterol (mmol/L)

5.04 ± 1.14

5.03 ± 1.65

4.85 ± 1.06

4.72 ± 0.72

5.20 ± 1.30

n.s.

S-HDL (mmol/L)

1.20 ± 0.31

1.25 ± 0.24

1.2 ± 0.29

1.09 ± 0.24

1.24 ± 0.48

n.s.

S-LDL (mmol/L)

2.98 ± 0.99

3.34 ± 1.08

3.02 ± 0.97

2.70 ± 0.71

3.03 ± 1.21

n.s.

S-Tg (mmol/L)

1.65 ± 1.12

1.17 ± 0.66

1.33 ± 0.68

2.17 ± 1.43

2.61 ± 1.52

<0.01

S-glucose (mmol/L)

5.13 ± 0.59

5.07 ± 0.45

5.18 ± 0.67

4.80 ± 0.67

5.18 ± 0.62

n.s.

  1. Values reported are mean ± SD. Linear trend between sex hormones and CKD staging was tested with one way ANOVA. Data were considered statistically significant at P < 0.05. The conversion factor for prolactin from mass to units is 21.2. ((μg/L) x 21.2 = mIU/L)